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Novas perspectivas de tratamento medicamentoso do diabetes mellitus / New prospects for drug treatment of diabetes mellitus
Sá, João Roberto de; Vidotto, Tiago Munhoz.
Affiliation
  • Sá, João Roberto de; UNIFESP. Escola Paulista de Medicina. Disciplina de Endocrinologia e Metabologia. BR
  • Vidotto, Tiago Munhoz; UNIFESP. Escola Paulista de Medicina. Disciplina de Medicina de Urgência. BR
J. bras. med ; 100(4): 7-12, Set.-Out. 2012. tab
Article in Portuguese | LILACS | ID: lil-670536
Responsible library: BR1365.1
RESUMO
O diabetes mellitus tipo 2 (DM2) apresenta alta prevalência, com aumento inclusive em crianças e adolescentes. A importância de um estrito controle glicêmico pode ser comprovada com a redução das complicações crônicas microvasculares. Já em relação à redução da doença macrovascular, principal causa de mortalidade nestes pacientes, são fundamentais o controle da glicemia, bem como de outros fatores de risco cardiovasculares, tais como hipertensão arterial, dislipidemia, peso, e a manutenção de hábitos saudáveis de vida. Temos vários medicamentos para o tratamento do DM2, sendo que a metformina é ainda a droga de primeira escolha, devido ao seu baixo custo e eficácia comprovada.
ABSTRACT
Type 2 diabetes mellitus (DM2) is highly prevalent and is increasing even in children and adolescents. The importance of strict glycemic control can be proven to reduce chronic microvascular complications. Regarding the reduction of macrovascular disease, the leading cause of mortality in these patients, it is essential tight glycemic control, as well as other cardiovascular risk factors, such as arterial hypertension, dyslipidemia, weight control, and maintaining healthy lifestyles. We have a lot of drugs for the treatment of DM2, and metformin is still the drug of first choice due to its low cost and proven effectiveness.
Subject(s)

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Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.4: Reduce premature mortality due to noncommunicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Diabetes Mellitus / Endocrine System Diseases / Noncommunicable Diseases Database: LILACS Main subject: Glycemic Index / Metformin Type of study: Risk factors Limits: Female / Humans / Male Language: Portuguese Journal: J. bras. med Journal subject: Medicine Year: 2012 Document type: Article Affiliation country: Brazil Institution/Affiliation country: UNIFESP/BR
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Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.4: Reduce premature mortality due to noncommunicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Diabetes Mellitus / Endocrine System Diseases / Noncommunicable Diseases Database: LILACS Main subject: Glycemic Index / Metformin Type of study: Risk factors Limits: Female / Humans / Male Language: Portuguese Journal: J. bras. med Journal subject: Medicine Year: 2012 Document type: Article Affiliation country: Brazil Institution/Affiliation country: UNIFESP/BR
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