Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa / Initial resuscitation bundle and monitoring tissue perfusion in severe sepsis
Rev. méd. Chile
; 141(9): 1173-1181, set. 2013. tab
Article
in Spanish
| LILACS
| ID: lil-699685
Responsible library:
CL1.1
ABSTRACT
Sepsis is a global health problem. Despite recent advances in understanding its pathophysiology and clinical trials testing potential new therapies, mortality remains unacceptably high. In fact, sepsis is the leading cause of death in non-coronary intensive care units around the world. However, during the past decade, some studies have highlighted that early recognition of sepsis and an appropriate initial approach are fundamental determinants of prognosis. A systematic approach to the harmful triad of sepsis-related hypotension, tissue hypoperfusion and organ dysfunction, with low-cost, easy to implement, and effective interventions, can significantly improve the chances of survival. In this article, we will update the evidence supporting the initial resuscitation bundle for patients with severe sepsis, and discuss the physiological basis for perfusion monitoring during septic shock resuscitation.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Target 3.8 Achieve universal access to health
/
SDG3 - Health and Well-Being
Health problem:
Delivery Arrangements
/
Target 3.8 Achieve universal access to health
Database:
LILACS
Main subject:
Resuscitation
/
Sepsis
Type of study:
Prognostic study
/
Systematic review
Limits:
Humans
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2013
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Clínico Universidad de Chile/CL