In vitro study of two dominant inhibitory GTPase mutants of Escherichia coli translation initiation factor IF2. Direct evidence that GTP hydrolysis is necessary for factor recycling.

Luchin, S; Putzer, H; Hershey, J W; Cenatiempo, Y; Grunberg-Manago, M; Laalami, S

Luchin, S; Putzer, H; Hershey, J W; Cenatiempo, Y; Grunberg-Manago, M; Laalami, S.

Affiliation

Luchin S; UPR9073 du CNRS, Institut de Biologie Physico-Chimique 13, rue Pierre et Marie Curie, 75005 Paris, France.

J Biol Chem ; 274(10): 6074-9, 1999 Mar 05.

Article in En | MEDLINE | ID: mdl-10037688

Subject(s)

Escherichia coli/genetics; Gene Expression Regulation, Bacterial; Mutation; Peptide Initiation Factors/genetics; Escherichia coli/growth & development; GTP Phosphohydrolases/genetics; GTP Phosphohydrolases/metabolism; Hydrolysis; Peptide Initiation Factors/metabolism; Prokaryotic Initiation Factor-2

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Bacterial / Peptide Initiation Factors / Escherichia coli / Mutation Language: En Journal: J Biol Chem Year: 1999 Document type: Article Affiliation country: France Country of publication: United States

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