Effects of the ionophore antibiotic monensin on hepatic biotransformations and target organ morphology in rats.

Dacasto, M; Ceppa, L; Cornaglia, E; Valenza, F; Carletti, M; Bosio, A; Bosia, S; Ugazio, G; Nebbia, C

Dacasto, M; Ceppa, L; Cornaglia, E; Valenza, F; Carletti, M; Bosio, A; Bosia, S; Ugazio, G; Nebbia, C.

Affiliation

Dacasto M; Dipartimento di Patologia Animale, Settore di Farmacologia e Tossicologia, Università degli Studi di Torino, via Nizza 52, Torino, 10126, Italy.

Pharmacol Res ; 39(1): 5-10, 1999 Jan.

Article in En | MEDLINE | ID: mdl-10051372

Subject(s)

Antiprotozoal Agents/toxicity; Biotransformation/drug effects; Heart/drug effects; Liver/drug effects; Mitochondria/drug effects; Monensin/toxicity; Muscle, Skeletal/drug effects; Animals; Body Weight/drug effects; Creatine Kinase/blood; Cytochrome P-450 Enzyme System/drug effects; Cytochrome P-450 Enzyme System/metabolism; Glutathione/drug effects; Glutathione/metabolism; L-Lactate Dehydrogenase/blood; Liver/enzymology; Male; Organ Size/drug effects; Pharmaceutical Preparations/metabolism; Rats; Rats, Wistar

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Collection: 01-internacional Database: MEDLINE Main subject: Biotransformation / Monensin / Muscle, Skeletal / Heart / Liver / Mitochondria / Antiprotozoal Agents Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 1999 Document type: Article Affiliation country: Italy Country of publication: Netherlands

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