VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling.

Gupta, K; Kshirsagar, S; Li, W; Gui, L; Ramakrishnan, S; Gupta, P; Law, P Y; Hebbel, R P

Gupta, K; Kshirsagar, S; Li, W; Gui, L; Ramakrishnan, S; Gupta, P; Law, P Y; Hebbel, R P.

Affiliation

Gupta K; Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, 55455, USA. gupta014@gold.tc.umn.edu

Exp Cell Res ; 247(2): 495-504, 1999 Mar 15.

Article in En | MEDLINE | ID: mdl-10066377

Subject(s)

Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases/metabolism; Endothelial Growth Factors/metabolism; Lymphokines/metabolism; Mitogen-Activated Protein Kinases; Signal Transduction; Capillaries; Ceramides/pharmacology; DNA Fragmentation; Endothelial Growth Factors/pharmacology; Endothelium, Vascular/cytology; Humans; JNK Mitogen-Activated Protein Kinases; Lymphokines/pharmacology; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Endothelial Growth Factors / Lymphokines / Apoptosis / Calcium-Calmodulin-Dependent Protein Kinases / Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: Exp Cell Res Year: 1999 Document type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links