Cellular and biochemical response of the human lung after intrapulmonary instillation of ferric oxide particles.

Lay, J C; Bennett, W D; Ghio, A J; Bromberg, P A; Costa, D L; Kim, C S; Koren, H S; Devlin, R B

Lay, J C; Bennett, W D; Ghio, A J; Bromberg, P A; Costa, D L; Kim, C S; Koren, H S; Devlin, R B.

Affiliation

Lay JC; Center for Environmental Medicine and Lung Biology, University of North Carolina, Chapel Hill 27599-7310, USA.

Am J Respir Cell Mol Biol ; 20(4): 631-42, 1999 Apr.

Article in En | MEDLINE | ID: mdl-10100994

Subject(s)

Ferric Compounds/toxicity; Inflammation/physiopathology; Lung/drug effects; Macrophages, Alveolar/physiology; Neutrophils/physiology; Adult; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid/chemistry; Bronchoalveolar Lavage Fluid/cytology; Dinoprostone/analysis; Female; Ferric Compounds/administration & dosage; Humans; Inflammation/chemically induced; Instillation, Drug; Interleukin-8/analysis; Iron/administration & dosage; Iron/pharmacology; L-Lactate Dehydrogenase/analysis; Leukotriene C4/analysis; Leukotriene E4/analysis; Lung/pathology; Lung/physiopathology; Macrophages, Alveolar/drug effects; Macrophages, Alveolar/pathology; Male; Neutrophils/drug effects; Neutrophils/pathology; Phagocytosis; Rats; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Ferric Compounds / Macrophages, Alveolar / Inflammation / Lung / Neutrophils Type of study: Clinical_trials Limits: Adult / Animals / Female / Humans / Male Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 1999 Document type: Article Affiliation country: United States Country of publication: United States

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