Activation of nuclear factor-kappaB by lipopolysaccharide in mononuclear leukocytes is prevented by inhibitors of cytosolic phospholipase A2.

Burgermeister, E; Tibes, U; Stockinger, H; Scheuer, W V

Burgermeister, E; Tibes, U; Stockinger, H; Scheuer, W V.

Affiliation

Burgermeister E; Department of Molecular Pharmacology, Roche Diagnostics, Penzberg, Germany.

Eur J Pharmacol ; 369(3): 373-86, 1999 Mar 26.

Article in En | MEDLINE | ID: mdl-10225377

Subject(s)

Hydrocarbons, Fluorinated/pharmacology; Interleukin-1/genetics; Ketones/pharmacology; Lipopolysaccharides/pharmacology; NF-kappa B/metabolism; Phospholipases A/antagonists & inhibitors; Transcription, Genetic/drug effects; Animals; Cytosol/drug effects; Cytosol/enzymology; DNA Probes; Flow Cytometry; Humans; Interleukin-1/biosynthesis; Interleukin-1/isolation & purification; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/metabolism; Mice; Phospholipases A/metabolism; Phospholipases A2; RNA, Messenger/genetics; Reverse Transcriptase Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: Phospholipases A / Transcription, Genetic / Lipopolysaccharides / NF-kappa B / Interleukin-1 / Hydrocarbons, Fluorinated / Ketones Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 1999 Document type: Article Affiliation country: Germany Country of publication: Netherlands

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