Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes.

Ferrarini, M; Imro, M A; Sciorati, C; Heltai, S; Protti, M P; Pellicciari, C; Rovere, P; Manfredi, A A; Rugarli, C

Ferrarini, M; Imro, M A; Sciorati, C; Heltai, S; Protti, M P; Pellicciari, C; Rovere, P; Manfredi, A A; Rugarli, C.

Affiliation

Ferrarini M; Laboratorio di Immunologia dei Tumori, Divisione di Medicina II, H San Raffaele Scientific Institute, Milan, Italy. ferrarini.m@hsr.it

Int J Cancer ; 81(4): 573-9, 1999 May 17.

Article in En | MEDLINE | ID: mdl-10225447

Subject(s)

Melanoma/immunology; Membrane Glycoproteins/physiology; Signal Transduction/immunology; T-Lymphocytes, Cytotoxic/immunology; fas Receptor/physiology; Antigens, CD/immunology; Apoptosis; Cells, Cultured; Clone Cells; Coculture Techniques; Cytotoxicity, Immunologic; Fas Ligand Protein; Flow Cytometry; Humans; Interleukin-2/pharmacology; Interleukin-2/physiology; Jurkat Cells; Lymphocyte Activation; Melanoma/pathology; Membrane Glycoproteins/genetics; Receptors, Antigen, T-Cell, gamma-delta/immunology; Skin Neoplasms/immunology; Skin Neoplasms/pathology; Tumor Cells, Cultured; fas Receptor/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / T-Lymphocytes, Cytotoxic / Signal Transduction / Fas Receptor / Melanoma Limits: Humans Language: En Journal: Int J Cancer Year: 1999 Document type: Article Affiliation country: Italy Country of publication: United States

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