Tumor-enhancing effects of cholic acid are exerted on the early stages of colon carcinogenesis via induction of aberrant crypt foci with an enhanced growth phenotype.

Baijal, P K; Clow, E P; Fitzpatrick, D W; Bird, R P

Baijal, P K; Clow, E P; Fitzpatrick, D W; Bird, R P.

Affiliation

Baijal PK; Department of Foods and Nutrition, University of Manitoba, Winnipeg, Canada.

Can J Physiol Pharmacol ; 76(12): 1095-102, 1998 Dec.

Article in En | MEDLINE | ID: mdl-10326831

Subject(s)

Bile Acids and Salts/pharmacology; Carcinogens/pharmacology; Cholic Acid/pharmacology; Colon/drug effects; Colonic Neoplasms/chemically induced; Precancerous Conditions/chemically induced; Animals; Azoxymethane; Drug Synergism; Male; Rats; Rats, Sprague-Dawley; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Bile Acids and Salts / Carcinogens / Colon / Colonic Neoplasms / Cholic Acid Limits: Animals Language: En Journal: Can J Physiol Pharmacol Year: 1998 Document type: Article Affiliation country: Canada Country of publication: Canada

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