Radioligand assays for oestradiol and progesterone conjugated to protein reveal evidence for a common membrane binding site in the medial preoptic area-anterior hypothalamus and differential modulation by cholera toxin and GTPgammaS.

Caldwell, J D; Walker, C H; Rivkina, A; Pedersen, C A; Mason, G A

Caldwell, J D; Walker, C H; Rivkina, A; Pedersen, C A; Mason, G A.

Affiliation

Caldwell JD; Department of Pharmaceutical Sciences, North Dakota State University, Fargo, ND 58105-5055, USA. jcaldwell@plains.nodak.edu

J Neuroendocrinol ; 11(6): 409-17, 1999 Jun.

Article in En | MEDLINE | ID: mdl-10336721

Subject(s)

Cholera Toxin/pharmacology; Estradiol/metabolism; Guanosine 5'-O-(3-Thiotriphosphate)/pharmacology; Progesterone/metabolism; Animals; Binding Sites/drug effects; Binding, Competitive/drug effects; Female; GTP-Binding Proteins/metabolism; Hypothalamus, Anterior/drug effects; Hypothalamus, Anterior/metabolism; Kinetics; Membranes/drug effects; Membranes/metabolism; Ovariectomy; Preoptic Area/drug effects; Preoptic Area/metabolism; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated

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Collection: 01-internacional Database: MEDLINE Main subject: Progesterone / Cholera Toxin / Guanosine 5'-O-(3-Thiotriphosphate) / Estradiol Limits: Animals Language: En Journal: J Neuroendocrinol Journal subject: ENDOCRINOLOGIA / NEUROLOGIA Year: 1999 Document type: Article Affiliation country: United States Country of publication: United States

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