Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kappaB elements.

Farina, A R; Tacconelli, A; Vacca, A; Maroder, M; Gulino, A; Mackay, A R

Farina, A R; Tacconelli, A; Vacca, A; Maroder, M; Gulino, A; Mackay, A R.

Affiliation

Farina AR; Department of Experimental Medicine, University of L'Aquila, Coppito Il, Italy.

Cell Growth Differ ; 10(5): 353-67, 1999 May.

Article in En | MEDLINE | ID: mdl-10359016

Subject(s)

Collagenases/genetics; NF-kappa B/metabolism; Neoplasm Invasiveness; Neuroblastoma/pathology; Neurons/cytology; Transcription, Genetic; Up-Regulation; Benzoquinones; Binding Sites; CSK Tyrosine-Protein Kinase; Cell Extracts; Cell Nucleus/metabolism; Collagenases/physiology; Enzyme Inhibitors/pharmacology; Epithelial Cells; Humans; Lactams, Macrocyclic; Matrix Metalloproteinase 9; Phenotype; Promoter Regions, Genetic; Protein-Tyrosine Kinases/antagonists & inhibitors; Protein-Tyrosine Kinases/metabolism; Quinones/pharmacology; Response Elements; Rifabutin/analogs & derivatives; Sp1 Transcription Factor/metabolism; Transcription Factor AP-1/metabolism; Transcriptional Activation; Tumor Cells, Cultured; src-Family Kinases

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Up-Regulation / NF-kappa B / Collagenases / Neoplasm Invasiveness / Neuroblastoma / Neurons Limits: Humans Language: En Journal: Cell Growth Differ Journal subject: BIOLOGIA MOLECULAR Year: 1999 Document type: Article Affiliation country: Italy Country of publication: United States

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