A large subset of neutrophils expressing membrane proteinase 3 is a risk factor for vasculitis and rheumatoid arthritis.

Witko-Sarsat, V; Lesavre, P; Lopez, S; Bessou, G; Hieblot, C; Prum, B; Noël, L H; Guillevin, L; Ravaud, P; Sermet-Gaudelus, I; Timsit, J; Grünfeld, J P; Halbwachs-Mecarelli, L

Witko-Sarsat, V; Lesavre, P; Lopez, S; Bessou, G; Hieblot, C; Prum, B; Noël, L H; Guillevin, L; Ravaud, P; Sermet-Gaudelus, I; Timsit, J; Grünfeld, J P; Halbwachs-Mecarelli, L.

Affiliation

Witko-Sarsat V; Institut National de la Santé et de la Recherche Médicale U507 and Department of Nephrology, Necker Hospital, Paris, France. witko-sarsat@necker.fr

J Am Soc Nephrol ; 10(6): 1224-33, 1999 Jun.

Article in En | MEDLINE | ID: mdl-10361860

Subject(s)

Antibodies, Antineutrophil Cytoplasmic/metabolism; Arthritis, Rheumatoid/genetics; Autoimmune Diseases/genetics; Neutrophils/enzymology; Serine Endopeptidases/genetics; Serine Endopeptidases/metabolism; Vasculitis/genetics; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic/genetics; Arthritis, Rheumatoid/immunology; Autoimmune Diseases/immunology; Cystic Fibrosis/genetics; Diabetes Mellitus, Type 1/genetics; Female; Flow Cytometry; Gene Expression; Humans; Male; Middle Aged; Myeloblastin; Neutrophils/immunology; Pedigree; Phenotype; Reference Values; Risk Factors; Sensitivity and Specificity; Vasculitis/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Autoimmune Diseases / Vasculitis / Serine Endopeptidases / Antibodies, Antineutrophil Cytoplasmic / Neutrophils Type of study: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Am Soc Nephrol Journal subject: NEFROLOGIA Year: 1999 Document type: Article Affiliation country: France Country of publication: United States

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