The phosphoinositide 3-kinase/Akt pathway is activated by daunorubicin in human acute myeloid leukemia cell lines.

Plo, I; Bettaïeb, A; Payrastre, B; Mansat-De Mas, V; Bordier, C; Rousse, A; Kowalski-Chauvel, A; Laurent, G; Lautier, D

Plo, I; Bettaïeb, A; Payrastre, B; Mansat-De Mas, V; Bordier, C; Rousse, A; Kowalski-Chauvel, A; Laurent, G; Lautier, D.

Affiliation

Plo I; INSERM E9910, Institut Claudius Rëguad, Toulouse, France.

FEBS Lett ; 452(3): 150-4, 1999 Jun 11.

Article in En | MEDLINE | ID: mdl-10386580

Subject(s)

Daunorubicin/pharmacology; Phosphatidylinositol 3-Kinases/metabolism; Acute Disease; Androstadienes/pharmacology; Apoptosis; Ceramides/metabolism; Chromones/pharmacology; Enzyme Activation; Enzyme Inhibitors/pharmacology; Humans; Kinetics; Leukemia, Myeloid; Morpholines/pharmacology; Phosphatidylinositol Phosphates/metabolism; U937 Cells; Wortmannin

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Collection: 01-internacional Database: MEDLINE Main subject: Daunorubicin / Phosphatidylinositol 3-Kinases Limits: Humans Language: En Journal: FEBS Lett Year: 1999 Document type: Article Affiliation country: France Country of publication: United kingdom

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