Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2.

Chuntharapai, A; Gibbs, V; Lu, J; Ow, A; Marsters, S; Ashkenazi, A; De Vos, A; Jin Kim, K

Chuntharapai, A; Gibbs, V; Lu, J; Ow, A; Marsters, S; Ashkenazi, A; De Vos, A; Jin Kim, K.

Affiliation

Chuntharapai A; Department of Antibody Technology, Genentech Inc., South San Francisco, CA 94080, USA.

J Immunol ; 163(2): 766-73, 1999 Jul 15.

Article in En | MEDLINE | ID: mdl-10395669

Subject(s)

Amino Acids/metabolism; Interferon Type I/metabolism; Receptors, Interferon/metabolism; Signal Transduction/immunology; Amino Acid Substitution/genetics; Amino Acids/genetics; Amino Acids/immunology; Animals; Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/pharmacology; Binding Sites, Antibody/genetics; Binding, Competitive/genetics; Binding, Competitive/immunology; Cell Line; HeLa Cells; Humans; L Cells; Ligands; Membrane Proteins; Mice; Mice, Inbred BALB C; Models, Molecular; Protein Binding/genetics; Protein Binding/immunology; Receptor, Interferon alpha-beta; Receptors, Interferon/immunology; Receptors, Interferon/physiology; Signal Transduction/genetics; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Interferon Type I / Receptors, Interferon / Amino Acids Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Immunol Year: 1999 Document type: Article Affiliation country: United States Country of publication: United States

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