Dual mode of stimulation by the beta-carboline ZK 91085 of recombinant GABA(A) receptor currents: molecular determinants affecting its action.

Thomet, U; Baur, R; Scholze, P; Sieghart, W; Sigel, E

Thomet, U; Baur, R; Scholze, P; Sieghart, W; Sigel, E.

Affiliation

Thomet U; Department of Pharmacology, University of Bern, Switzerland.

Br J Pharmacol ; 127(5): 1231-9, 1999 Jul.

Article in En | MEDLINE | ID: mdl-10455270

Subject(s)

Carbolines/pharmacology; GABA Modulators/pharmacology; Receptors, GABA-A/drug effects; Animals; Dose-Response Relationship, Drug; Flunitrazepam/metabolism; Point Mutation; Rats; Recombinant Proteins/drug effects; Structure-Activity Relationship; Xenopus laevis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbolines / Receptors, GABA-A / GABA Modulators Limits: Animals Language: En Journal: Br J Pharmacol Year: 1999 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom

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