A combination of megakaryocyte growth and development factor and interleukin-1 is sufficient to culture large numbers of megakaryocytic progenitors and megakaryocytes for transfusion purposes.

van den Oudenrijn, S; de Haas, M; Calafat, J; van der Schoot, C E; von dem Borne, A E

van den Oudenrijn, S; de Haas, M; Calafat, J; van der Schoot, C E; von dem Borne, A E.

Affiliation

van den Oudenrijn S; Department of Experimental Immunohaematology, CLB and Laboratory of Experimental and Clinical Immunology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

Br J Haematol ; 106(2): 553-63, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10460622

Subject(s)

Hematopoietic Stem Cell Mobilization/methods; Interleukin-1/therapeutic use; Megakaryocytes/cytology; Thrombopoietin/therapeutic use; Antigens, CD34/analysis; Cell Count; Cell Division; Cells, Cultured; Drug Combinations; Flow Cytometry; Hematopoietic Stem Cell Transplantation/methods; Humans; Microscopy, Immunoelectron; Phenotype; Platelet Glycoprotein GPIIb-IIIa Complex/analysis; Ploidies

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Collection: 01-internacional Database: MEDLINE Main subject: Thrombopoietin / Megakaryocytes / Interleukin-1 / Hematopoietic Stem Cell Mobilization Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Br J Haematol Year: 1999 Document type: Article Affiliation country: Netherlands

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