Human serum Paraoxonase/Arylesterase's retained hydrophobic N-terminal leader sequence associates with HDLs by binding phospholipids : apolipoprotein A-I stabilizes activity.

Sorenson, R C; Bisgaier, C L; Aviram, M; Hsu, C; Billecke, S; La Du, B N

Sorenson, R C; Bisgaier, C L; Aviram, M; Hsu, C; Billecke, S; La Du, B N.

Affiliation

Sorenson RC; Department of Pharmacology, University of Michigan Medical School, Ann Arbor 48109, USA.

Arterioscler Thromb Vasc Biol ; 19(9): 2214-25, 1999 Sep.

Article in En | MEDLINE | ID: mdl-10479665

Subject(s)

Apolipoprotein A-I/physiology; Carboxylic Ester Hydrolases/metabolism; Cholesterol, HDL/metabolism; Esterases/metabolism; Peptide Fragments/metabolism; Phospholipids/metabolism; Animals; Aryldialkylphosphatase; Binding, Competitive; Carboxylic Ester Hydrolases/blood; Carboxylic Ester Hydrolases/genetics; Carboxylic Ester Hydrolases/physiology; Cell Line; Detergents/metabolism; Esterases/blood; Esterases/genetics; Esterases/physiology; Female; Humans; Lipoproteins/blood; Lipoproteins/metabolism; Lipoproteins, LDL/metabolism; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Peptide Fragments/genetics; Peptide Fragments/physiology; Phospholipids/pharmacology; Proteolipids/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Phospholipids / Carboxylic Ester Hydrolases / Apolipoprotein A-I / Esterases / Cholesterol, HDL Type of study: Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 1999 Document type: Article Affiliation country: United States

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