A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity.
J Med Chem
; 42(19): 3785-8, 1999 Sep 23.
Article
in En
| MEDLINE
| ID: mdl-10508427
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phenylurea Compounds
/
Transcription Factors
/
Butyrates
/
Nuclear Proteins
/
Zinc Fingers
/
Receptors, Cytoplasmic and Nuclear
/
DNA-Binding Proteins
/
Lipid Metabolism
/
Hypolipidemic Agents
Limits:
Animals
/
Humans
/
Male
Language:
En
Journal:
J Med Chem
Journal subject:
QUIMICA
Year:
1999
Document type:
Article
Affiliation country:
United States