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Genes encoding acyl-CoA dehydrogenase (AcdH) homologues from Streptomyces coelicolor and Streptomyces avermitilis provide insights into the metabolism of small branched-chain fatty acids and macrolide antibiotic production.
Zhang, Ying-Xin; Denoya, Claudio D; Skinner, Deborah D; Fedechko, Ronald W; McArthur, Hamish A I; Morgenstern, Margaret R; Davies, Richard A; Lobo, Sandra; Reynolds, Kevin A; Hutchinson, C Richard.
Affiliation
  • Zhang YX; School of Pharmacy1 and Department of Bacteriology2, University of Wisconsin, 425 N. Charter St, Madison, WI 53706, USA.
  • Denoya CD; Bioprocess Research, Central Research Division, Pfizer Inc., Groton, CT 06340, USA3.
  • Skinner DD; Bioprocess Research, Central Research Division, Pfizer Inc., Groton, CT 06340, USA3.
  • Fedechko RW; Bioprocess Research, Central Research Division, Pfizer Inc., Groton, CT 06340, USA3.
  • McArthur HAI; Bioprocess Research, Central Research Division, Pfizer Inc., Groton, CT 06340, USA3.
  • Morgenstern MR; Bioprocess Research, Central Research Division, Pfizer Inc., Groton, CT 06340, USA3.
  • Davies RA; Bioprocess Research, Central Research Division, Pfizer Inc., Groton, CT 06340, USA3.
  • Lobo S; Department of Medicinal Chemistry, School of Pharmacy and Institute for Structural Biology and Drug Discovery, Virginia Commonwealth University, Richmond, VA 23219, USA4.
  • Reynolds KA; Department of Medicinal Chemistry, School of Pharmacy and Institute for Structural Biology and Drug Discovery, Virginia Commonwealth University, Richmond, VA 23219, USA4.
  • Hutchinson CR; School of Pharmacy1 and Department of Bacteriology2, University of Wisconsin, 425 N. Charter St, Madison, WI 53706, USA.
Microbiology (Reading) ; 145 ( Pt 9): 2323-2334, 1999 Sep.
Article in En | MEDLINE | ID: mdl-10517585

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptomyces / Acyl-CoA Dehydrogenases / Fatty Acids / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: Microbiology (Reading) Journal subject: MICROBIOLOGIA Year: 1999 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptomyces / Acyl-CoA Dehydrogenases / Fatty Acids / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: Microbiology (Reading) Journal subject: MICROBIOLOGIA Year: 1999 Document type: Article Affiliation country: United States Country of publication: United kingdom