Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors.

Marcus, V A; Madlensky, L; Gryfe, R; Kim, H; So, K; Millar, A; Temple, L K; Hsieh, E; Hiruki, T; Narod, S; Bapat, B V; Gallinger, S; Redston, M

Marcus, V A; Madlensky, L; Gryfe, R; Kim, H; So, K; Millar, A; Temple, L K; Hsieh, E; Hiruki, T; Narod, S; Bapat, B V; Gallinger, S; Redston, M.

Affiliation

Marcus VA; Department of Pathology, Samuel Lunenfeld Research Institute and Mount Sinai Hospital, Toronto, Canada.

Am J Surg Pathol ; 23(10): 1248-55, 1999 Oct.

Article in En | MEDLINE | ID: mdl-10524526

Subject(s)

Adenocarcinoma/genetics; Base Pair Mismatch/genetics; Colorectal Neoplasms/genetics; DNA Repair; DNA-Binding Proteins; Neoplasm Proteins/analysis; Proto-Oncogene Proteins/analysis; Adaptor Proteins, Signal Transducing; Adenocarcinoma/chemistry; Adenocarcinoma/pathology; Adult; Carrier Proteins; Colorectal Neoplasms/chemistry; Colorectal Neoplasms/pathology; DNA, Neoplasm/analysis; Genes, DCC/genetics; Genetic Predisposition to Disease/genetics; Humans; Immunoenzyme Techniques; Microsatellite Repeats/genetics; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Adenocarcinoma / Proto-Oncogene Proteins / Base Pair Mismatch / DNA-Binding Proteins / DNA Repair / Neoplasm Proteins Type of study: Prognostic_studies Limits: Adult / Humans Language: En Journal: Am J Surg Pathol Year: 1999 Document type: Article Affiliation country: Canada Country of publication: United States

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