The betaA4 amyloid peptide complexes to and enhances the uptake of beta-very low density lipoproteins by the low density lipoprotein receptor-related protein and heparan sulfate proteoglycans pathway.

Scharnagl, H; Tisljar, U; Winkler, K; Hüttinger, M; Nauck, M A; Gross, W; Wieland, H; Ohm, T G; März, W

Scharnagl, H; Tisljar, U; Winkler, K; Hüttinger, M; Nauck, M A; Gross, W; Wieland, H; Ohm, T G; März, W.

Affiliation

Scharnagl H; Department of Medicine, Albert Ludwigs-University, Freiburg, Germany. hubsch@med1.ukl.uni-freiburg.de

Lab Invest ; 79(10): 1271-86, 1999 Oct.

Article in En | MEDLINE | ID: mdl-10532590

Subject(s)

Amyloid beta-Peptides/chemistry; Heparan Sulfate Proteoglycans/metabolism; Lipoproteins, VLDL/metabolism; Receptors, LDL/metabolism; Animal Feed; Animals; CHO Cells; Cells, Cultured; Cholesterol, Dietary/pharmacology; Cricetinae; Fibroblasts/metabolism; Hippocampus/cytology; Hippocampus/metabolism; Humans; Lipoproteins, VLDL/chemistry; Low Density Lipoprotein Receptor-Related Protein-6; Rabbits; Rats; Rats, Wistar

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / Amyloid beta-Peptides / Heparan Sulfate Proteoglycans / Lipoproteins, VLDL Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Lab Invest Year: 1999 Document type: Article Affiliation country: Germany

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