Metabolism of tauromustine in liver and lung microsomes from various species.

Tuvesson, H; Gunnarsson, P O; Seidegård, J

Tuvesson, H; Gunnarsson, P O; Seidegård, J.

Affiliation

Tuvesson H; Pharmacokinetics and Metabolism, Active Biotech Research AB, Lund, Sweden. helen.tuvesson@activebiotech.com

Xenobiotica ; 29(8): 783-92, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10553719

Subject(s)

Aryl Hydrocarbon Hydroxylases; Lung/metabolism; Microsomes/metabolism; Nitrosourea Compounds/metabolism; Steroid 16-alpha-Hydroxylase; Taurine/analogs & derivatives; Animals; Cytochrome P-450 CYP1A2/genetics; Cytochrome P-450 CYP1A2/metabolism; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6/genetics; Cytochrome P-450 CYP2D6/metabolism; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System/drug effects; Cytochrome P-450 Enzyme System/genetics; Cytochrome P-450 Enzyme System/metabolism; Cytochromes; Dogs; Female; Humans; Male; Methylcholanthrene/pharmacology; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Microsomes, Liver/drug effects; Microsomes, Liver/metabolism; Mixed Function Oxygenases/genetics; Mixed Function Oxygenases/metabolism; Oxidoreductases, N-Demethylating/drug effects; Oxidoreductases, N-Demethylating/metabolism; Phenobarbital/pharmacology; Pregnenolone/analogs & derivatives; Rats; Rats, Sprague-Dawley; Species Specificity; Steroid Hydroxylases/genetics; Steroid Hydroxylases/metabolism; Taurine/metabolism; Testosterone/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Taurine / Aryl Hydrocarbon Hydroxylases / Steroid 16-alpha-Hydroxylase / Lung / Microsomes / Nitrosourea Compounds Language: En Journal: Xenobiotica Year: 1999 Document type: Article Affiliation country: Sweden Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links