Metabolism of furazolidone: alternative pathways and modes of toxicity in different cell lines.

De Angelis, I; Rossi, L; Pedersen, J Z; Vignoli, A L; Vincentini, O; Hoogenboom, L A; Polman, T H; Stammati, A; Zucco, F

De Angelis, I; Rossi, L; Pedersen, J Z; Vignoli, A L; Vincentini, O; Hoogenboom, L A; Polman, T H; Stammati, A; Zucco, F.

Affiliation

De Angelis I; Istituto Superiore di Sanità, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy.

Xenobiotica ; 29(11): 1157-69, 1999 Nov.

Article in En | MEDLINE | ID: mdl-10598749

Subject(s)

Anti-Infective Agents, Local/metabolism; Anti-Infective Agents, Local/toxicity; Furazolidone/metabolism; Furazolidone/toxicity; Biotransformation; Caco-2 Cells; Cell Division/physiology; Cell Hypoxia/physiology; Cell Line; Colony-Forming Units Assay; Electron Spin Resonance Spectroscopy; Free Radicals/metabolism; Glutathione/metabolism; Humans; Protein Binding

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Collection: 01-internacional Database: MEDLINE Main subject: Furazolidone / Anti-Infective Agents, Local Limits: Humans Language: En Journal: Xenobiotica Year: 1999 Document type: Article Affiliation country: Italy

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