HIV-1 Tat mutants in the cysteine-rich region downregulate HLA class II expression in T lymphocytic and macrophage cell lines.

Tosi, G; De Lerma Barbaro, A; D'Agostino, A; Valle, M T; Megiovanni, A M; Manca, F; Caputo, A; Barbanti-Brodano, G; Accolla, R S

Tosi, G; De Lerma Barbaro, A; D'Agostino, A; Valle, M T; Megiovanni, A M; Manca, F; Caputo, A; Barbanti-Brodano, G; Accolla, R S.

Affiliation

Tosi G; Department of Clinical and Biological Sciences School of Medicine, University of Insubria, Varese, Italy.

Eur J Immunol ; 30(1): 19-28, 2000 Jan.

Article in En | MEDLINE | ID: mdl-10602023

Subject(s)

Gene Products, tat/physiology; HIV-1/physiology; Histocompatibility Antigens Class II/biosynthesis; Macrophages/metabolism; Nuclear Proteins; T-Lymphocytes/metabolism; Antigen Presentation; Cell Line; Cysteine; Down-Regulation; Gene Expression Regulation; Histocompatibility Antigens Class I/biosynthesis; Histocompatibility Antigens Class II/genetics; Humans; Interferon-gamma/pharmacology; RNA, Messenger/analysis; Structure-Activity Relationship; Trans-Activators/genetics; tat Gene Products, Human Immunodeficiency Virus

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Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / T-Lymphocytes / Histocompatibility Antigens Class II / Gene Products, tat / HIV-1 / Macrophages Limits: Humans Language: En Journal: Eur J Immunol Year: 2000 Document type: Article Affiliation country: Italy Country of publication: Germany

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