Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases.

Ikematsu, N; Yoshida, Y; Kawamura-Tsuzuku, J; Ohsugi, M; Onda, M; Hirai, M; Fujimoto, J; Yamamoto, T

Ikematsu, N; Yoshida, Y; Kawamura-Tsuzuku, J; Ohsugi, M; Onda, M; Hirai, M; Fujimoto, J; Yamamoto, T.

Affiliation

Ikematsu N; Department of Oncology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

Oncogene ; 18(52): 7432-41, 1999 Dec 09.

Article in En | MEDLINE | ID: mdl-10602502

Subject(s)

CDC2-CDC28 Kinases; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism; Cyclin-Dependent Kinases/metabolism; Intracellular Signaling Peptides and Proteins; Proteins; Proto-Oncogene Proteins; Transcription Factors/metabolism; Tumor Suppressor Proteins; 3T3 Cells/cytology; 3T3 Cells/metabolism; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins/metabolism; Cell Line; Cloning, Molecular; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Exoribonucleases; G1 Phase/genetics; Gene Expression Profiling; Humans; Male; Mice; Molecular Sequence Data; Neoplasm Proteins/genetics; Protein Serine-Threonine Kinases/metabolism; Rabbits; Repressor Proteins; Ribonucleases; Sequence Homology, Amino Acid; Subcellular Fractions; Transcription Factors/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Proteins / Proto-Oncogene Proteins / Cyclin-Dependent Kinases / Cell Cycle Proteins / Tumor Suppressor Proteins / CDC2-CDC28 Kinases / Intracellular Signaling Peptides and Proteins Type of study: Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 1999 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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