Abasic site recognition in DNA as a new strategy to potentiate the action of anticancer alkylating drugs?

Belmont, P; Jourdan, M; Demeunynck, M; Constant, J F; Garcia, J; Lhomme, J; Carez, D; Croisy, A

Belmont, P; Jourdan, M; Demeunynck, M; Constant, J F; Garcia, J; Lhomme, J; Carez, D; Croisy, A.

Affiliation

Belmont P; INSERM U350, Institut Curie Recherche, Laboratoire Raymond Latarjet, Centre Universitaire, 91405 Orsay Cedex, France.

J Med Chem ; 42(25): 5153-9, 1999 Dec 16.

Article in En | MEDLINE | ID: mdl-10602700

Subject(s)

Antineoplastic Agents, Alkylating/metabolism; DNA, Neoplasm/metabolism; Animals; Antineoplastic Agents, Alkylating/chemistry; Antineoplastic Agents, Alkylating/pharmacology; Cattle; DNA, Neoplasm/chemistry; Drug Screening Assays, Antitumor; Female; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred DBA; Molecular Structure; Nucleic Acid Denaturation; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / Antineoplastic Agents, Alkylating Limits: Animals / Female / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1999 Document type: Article Affiliation country: France Country of publication: United States

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