High-level expression of I kappa B-beta in the surface epithelium of the colon: in vitro evidence for an immunomodulatory role.

Wu, G D; Huang, N; Wen, X; Keilbaugh, S A; Yang, H

Wu, G D; Huang, N; Wen, X; Keilbaugh, S A; Yang, H.

Affiliation

Wu GD; Department of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104-6144, USA. gdwu@mail.med.upenn.edu

J Leukoc Biol ; 66(6): 1049-56, 1999 Dec.

Article in En | MEDLINE | ID: mdl-10614789

Subject(s)

Adjuvants, Immunologic/physiology; Colon/immunology; Colon/metabolism; DNA-Binding Proteins/biosynthesis; DNA-Binding Proteins/immunology; I-kappa B Proteins; Animals; Butyric Acid/pharmacology; Caco-2 Cells; Cell Differentiation/physiology; Cell Nucleus/metabolism; Colon/drug effects; DNA-Binding Proteins/physiology; Epithelium/drug effects; Epithelium/immunology; Epithelium/metabolism; Humans; Interleukin-1/antagonists & inhibitors; Interleukin-1/pharmacology; Interleukin-8/biosynthesis; Interleukin-8/genetics; Intestinal Mucosa/drug effects; Intestinal Mucosa/immunology; Intestinal Mucosa/metabolism; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Promoter Regions, Genetic/physiology; Rats; Rats, Inbred F344; Transcriptional Activation/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Adjuvants, Immunologic / Colon / I-kappa B Proteins / DNA-Binding Proteins Limits: Animals / Humans Language: En Journal: J Leukoc Biol Year: 1999 Document type: Article Affiliation country: United States Country of publication: United kingdom

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