The suncus (Suncus murinus) shows poor metabolic phenotype for trimethylamine N-oxygenation.

Mushiroda, T; Yokoi, T; Takahara, E; Nagata, O; Kato, H; Kamataki, T

Mushiroda, T; Yokoi, T; Takahara, E; Nagata, O; Kato, H; Kamataki, T.

Affiliation

Mushiroda T; Laboratory of Drug Metabolism, Hokkaido University, Sapporo, Hokkaido, 060-0812, Japan.

Toxicol Appl Pharmacol ; 162(1): 44-8, 2000 Jan 01.

Article in En | MEDLINE | ID: mdl-10631126

Subject(s)

Methylamines/pharmacokinetics; Microsomes, Liver/metabolism; Oxygenases/physiology; Shrews/metabolism; Animals; Chromatography, Gas; Drug Interactions; Enzyme Inhibitors/pharmacology; In Vitro Techniques; Male; Methylamines/urine; Oxidation-Reduction; Oxygenases/antagonists & inhibitors; Phenotype; Rats; Rats, Sprague-Dawley

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Collection: 01-internacional Database: MEDLINE Main subject: Oxygenases / Shrews / Microsomes, Liver / Methylamines Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2000 Document type: Article Affiliation country: Japan

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