Prions: infectious proteins with genetic properties.
Biochemistry (Mosc)
; 64(12): 1382-90, 1999 Dec.
Article
in En
| MEDLINE
| ID: mdl-10648962
ABSTRACT
The data on prions--proteinaceous infectious agents--are briefly summarized. Prions cause several incurable neurodegenerative diseases in mammals, while in lower eukaryotes the prion properties of proteins may be responsible for the inheritance of some phenotypic traits. The novel experimental models for finding and studying proteins with prion properties based on the yeast Saccharomyces cerevisiae and the fungus Podospora anserina are described. The significance of the prion phenomenon for biology and medicine is discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prions
/
Saccharomyces cerevisiae Proteins
Type of study:
Etiology_studies
/
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Biochemistry (Mosc)
Year:
1999
Document type:
Article
Affiliation country:
RUSSIA