A role for smad6 in development and homeostasis of the cardiovascular system.

Galvin, K M; Donovan, M J; Lynch, C A; Meyer, R I; Paul, R J; Lorenz, J N; Fairchild-Huntress, V; Dixon, K L; Dunmore, J H; Gimbrone, M A; Falb, D; Huszar, D

Galvin, K M; Donovan, M J; Lynch, C A; Meyer, R I; Paul, R J; Lorenz, J N; Fairchild-Huntress, V; Dixon, K L; Dunmore, J H; Gimbrone, M A; Falb, D; Huszar, D.

Affiliation

Galvin KM; Millennium Pharmaceuticals, Cambridge, Massachusetts, USA. galvin@mpi.com

Nat Genet ; 24(2): 171-4, 2000 Feb.

Article in En | MEDLINE | ID: mdl-10655064

Subject(s)

Cardiovascular Abnormalities/genetics; Cardiovascular System/embryology; Cardiovascular System/growth & development; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Muscle, Smooth, Vascular/physiology; Signal Transduction/physiology; Trans-Activators/genetics; Trans-Activators/metabolism; Animals; DNA-Binding Proteins/deficiency; Female; Genomic Library; Homeostasis; Homozygote; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular/pathology; Mutagenesis, Insertional; Recombinant Fusion Proteins/metabolism; Restriction Mapping; Smad6 Protein; Trans-Activators/deficiency

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Collection: 01-internacional Database: MEDLINE Main subject: Cardiovascular System / Signal Transduction / Trans-Activators / Cardiovascular Abnormalities / DNA-Binding Proteins / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

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