Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1.

Lian, L Y; Barsukov, I; Golovanov, A P; Hawkins, D I; Badii, R; Sze, K H; Keep, N H; Bokoch, G M; Roberts, G C

Lian, L Y; Barsukov, I; Golovanov, A P; Hawkins, D I; Badii, R; Sze, K H; Keep, N H; Bokoch, G M; Roberts, G C.

Affiliation

Lian LY; Department of Biochemistry and Biological NMR Centre, University of Leicester, Leicester, LE1 7RH, UK. yun@le.ac.uk

Structure ; 8(1): 47-55, 2000 Jan 15.

Article in En | MEDLINE | ID: mdl-10673424

Subject(s)

Guanine Nucleotide Dissociation Inhibitors/chemistry; Guanine Nucleotide Dissociation Inhibitors/metabolism; rac1 GTP-Binding Protein/antagonists & inhibitors; rac1 GTP-Binding Protein/metabolism; Amino Acid Sequence; Animals; Binding Sites/genetics; Guanine Nucleotide Dissociation Inhibitors/genetics; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins/chemistry; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Sequence Homology, Amino Acid; Thermodynamics; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors

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Collection: 01-internacional Database: MEDLINE Main subject: Rac1 GTP-Binding Protein / Guanine Nucleotide Dissociation Inhibitors Limits: Animals / Humans Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2000 Document type: Article Affiliation country: United kingdom

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