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Walking with labor epidural analgesia: the impact of bupivacaine concentration and a lidocaine-epinephrine test dose.
Cohen, S E; Yeh, J Y; Riley, E T; Vogel, T M.
Affiliation
  • Cohen SE; Department of Anesthesia, Stanford University School of Medicine, California 94305, USA. secohen@leland.stanford.edu
Anesthesiology ; 92(2): 387-92, 2000 Feb.
Article in En | MEDLINE | ID: mdl-10691224
ABSTRACT

BACKGROUND:

Regional analgesia techniques for labor that permit ambulation are popular among parturients. This study evaluated the influence of bupivacaine bolus concentration and a 3-ml 1.5% lidocaine-epinephrine test dose, on analgesic effectiveness and the ability to walk after block placement.

METHODS:

Using a randomized double-blind study design, epidural analgesia was initiated in 60 parturients undergoing labor as follows Group TD/B.0625 received a 3-ml lidocaine-epinephrine test dose + 12 ml bupivacaine, 0.0625%; group TD/B.125 received a 3-ml test dose + 12 ml bupivacaine, 0.125%; group B.0625 received 15 ml bupivacaine, 0.0625% (no test dose); and group B.125 received 15 ml bupivacaine, 0.125% (no test dose). Initial boluses in all groups contained 10 microg sufentanil. Bupivacaine, 0.0625%, with 0.33 microg/ml sufentanil was infused throughout labor at 13.5-15 ml/h. Analgesia balance, proprioception, motor block, and patient ability to stand and walk were evaluated at various intervals.

RESULTS:

A bolus of 0.125% bupivacaine containing sufentanil, without a previous test dose, proved to be optimal with respect to analgesia and early ambulation. When a test dose was given before bupivacaine, 0.125%, fewer women walked within 1 h of block placement. Bupivacaine, 0.0625%, with sufentanil, with or without a test dose, provided inadequate analgesia, necessitating additional bupivacaine, which impaired the ability to walk. A high percentage of women in all groups (73-93%) walked at some stage during labor.

CONCLUSIONS:

Omitting a lidocaine-epinephrine test dose and using 0.125% bupivacaine for the initial bolus should permit ambulation in the early postblock period for most parturients who elect this option.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Vasoconstrictor Agents / Bupivacaine / Analgesia, Epidural / Epinephrine / Analgesia, Obstetrical / Walking / Anesthetics, Local / Lidocaine Type of study: Clinical_trials Limits: Adult / Female / Humans / Pregnancy Language: En Journal: Anesthesiology Year: 2000 Document type: Article Affiliation country: United States Publication country: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA
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Collection: 01-internacional Database: MEDLINE Main subject: Vasoconstrictor Agents / Bupivacaine / Analgesia, Epidural / Epinephrine / Analgesia, Obstetrical / Walking / Anesthetics, Local / Lidocaine Type of study: Clinical_trials Limits: Adult / Female / Humans / Pregnancy Language: En Journal: Anesthesiology Year: 2000 Document type: Article Affiliation country: United States Publication country: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA