Prevention with tamoxifen or other hormones versus prophylactic surgery in BRCA1/2-positive women: a decision analysis.

Grann, V R; Jacobson, J S; Whang, W; Hershman, D; Heitjan, D F; Antman, K H; Neugut, A I

Grann, V R; Jacobson, J S; Whang, W; Hershman, D; Heitjan, D F; Antman, K H; Neugut, A I.

Affiliation

Grann VR; Herbert Irving Comprehensive Cancer Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

Cancer J Sci Am ; 6(1): 13-20, 2000.

Article in En | MEDLINE | ID: mdl-10696733

Subject(s)

Anticarcinogenic Agents/therapeutic use; Breast Neoplasms/epidemiology; Breast Neoplasms/genetics; Genes, BRCA1; Mastectomy; Mutation; Neoplasm Proteins/genetics; Ovarian Neoplasms/epidemiology; Ovarian Neoplasms/genetics; Ovariectomy; Tamoxifen/therapeutic use; Transcription Factors/genetics; Adult; Aged; BRCA2 Protein; Breast Neoplasms/prevention & control; Cohort Studies; Contraceptives, Oral/therapeutic use; Disease-Free Survival; Female; Humans; Markov Chains; Middle Aged; Monte Carlo Method; Ovarian Neoplasms/prevention & control; Quality of Life; Raloxifene Hydrochloride/therapeutic use; Risk Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Tamoxifen / Transcription Factors / Breast Neoplasms / Ovariectomy / Anticarcinogenic Agents / Genes, BRCA1 / Mastectomy / Mutation / Neoplasm Proteins Type of study: Clinical_trials / Etiology_studies / Health_economic_evaluation / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Cancer J Sci Am Journal subject: NEOPLASIAS Year: 2000 Document type: Article Affiliation country: United States

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