[EFR-like peptides and their receptors as prognostic factors for the survival of patients with non-small-cell lung cancer]. / Sistema EFR-podobnykh peptidov i ikh retseptorov kak faktor prognoza vyzhivaemosti bol'nykh nemelkokletochnym rakom lëgkogo.

ABSTRACT

The levels of EGFR and its ligands have been assayed in tumor and adjacent lung tissues in NSCLC patients. Both EGFR and EGF-like peptides were found in tumor more frequently than in unaltered tissue. It was shown (Kaplan-Meyer) that simultaneous expression of EGFR and its ligands in tumor and adjacent lung tissues was associated with lower overall and relapse-free survival in NSCLC patients.