Determination of bis(tributyltin) oxide by GC--MS with on-line hydride derivatization: application to drug substance analysis.

O'Brien, T P; Dowling, T M; Moeder, C W; Bicker, G R

O'Brien, T P; Dowling, T M; Moeder, C W; Bicker, G R.

Affiliation

O'Brien TP; Merck Research Laboratories, Rahway, NJ 07065-0914, USA.

J Pharm Biomed Anal ; 19(3-4): 327-33, 1999 Mar.

Article in En | MEDLINE | ID: mdl-10704098

Subject(s)

Borohydrides/chemistry; Drug Contamination/prevention & control; Gas Chromatography-Mass Spectrometry/methods; Organotin Compounds/analysis; Pharmaceutical Preparations/chemistry; Trialkyltin Compounds/analysis; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry/instrumentation; Maximum Allowable Concentration; Reproducibility of Results; Sensitivity and Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Organotin Compounds / Trialkyltin Compounds / Borohydrides / Pharmaceutical Preparations / Drug Contamination / Gas Chromatography-Mass Spectrometry Type of study: Diagnostic_studies / Evaluation_studies Language: En Journal: J Pharm Biomed Anal Year: 1999 Document type: Article Affiliation country: United States Country of publication: United kingdom

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