Comparative pharmacodynamics of gatifloxacin and ciprofloxacin in an in vitro dynamic model: prediction of equiefficient doses and the breakpoints of the area under the curve/MIC ratio.

Vostrov, S N; Kononenko, O V; Lubenko, I Y; Zinner, S H; Firsov, A A

Vostrov, S N; Kononenko, O V; Lubenko, I Y; Zinner, S H; Firsov, A A.

Affiliation

Vostrov SN; Division of Infectious Diseases, Roger Williams Medical Center, Rhode Island Hospital, Brown University, Providence, Rhode Island, USA.

Antimicrob Agents Chemother ; 44(4): 879-84, 2000 Apr.

Article in En | MEDLINE | ID: mdl-10722485

Subject(s)

Anti-Infective Agents/pharmacology; Anti-Infective Agents/pharmacokinetics; Bacteria/drug effects; Ciprofloxacin/pharmacology; Ciprofloxacin/pharmacokinetics; Fluoroquinolones; Anti-Infective Agents/administration & dosage; Area Under Curve; Ciprofloxacin/administration & dosage; Computer Simulation; Escherichia coli/drug effects; Gatifloxacin; Half-Life; Humans; Klebsiella pneumoniae/drug effects; Models, Biological; Staphylococcus aureus/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Ciprofloxacin / Fluoroquinolones / Anti-Infective Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2000 Document type: Article Affiliation country: United States

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