[Enalapril treatment of residual pulmonary hypertension in patients operated rheumatic mitral valve defects]. / Lechenie rezidual'noi legochnoi gipertenzii énalaprilom u bol'nykh, operirovannykh po povodu revmaticheskikh mitral'nykh porokov serdtsa.
Klin Med (Mosk)
; 78(2): 40-2, 2000.
Article
in Ru
| MEDLINE
| ID: mdl-10723151
ABSTRACT
A pilot trial of efficiency of enalapril maleate in the treatment of residual pulmonary hypertension was made in 22 patients operated for rheumatic mitral valve defects. Degree I, II and III of pulmonary hypertension was registered in 5, 13 and 4 patients, respectively. Thus, the patients had NYHA functional classes III and IV (22.7 and 77.3%, respectively. Enalapril given for 6 months in a mean daily dose 12.3 +/- 1.57 mg/m2 (5-30 mg a day) normalized pressure in the pulmonary artery in 18.2% of patients. 50% of patients showed hypertension degree I, only one female retained hypertension degree III. To the end of the treatment the functional classes were the following II--in 68.2%, III--in 27.3% and IV--in 4.5%.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rheumatic Heart Disease
/
Angiotensin-Converting Enzyme Inhibitors
/
Enalapril
/
Hypertension, Pulmonary
/
Mitral Valve
Type of study:
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Ru
Journal:
Klin Med (Mosk)
Year:
2000
Document type:
Article