Endogenous oxygen radicals modulate protein tyrosine phosphorylation and JNK-1 activation in lectin-stimulated thymocytes.

Pani, G; Colavitti, R; Borrello, S; Galeotti, T

Pani, G; Colavitti, R; Borrello, S; Galeotti, T.

Affiliation

Pani G; Institute of General Pathology, Catholic University Medical School, Largo F. Vito 1, 00168 Rome, Italy. ibipg@rm.unicatt.it

Biochem J ; 347 Pt 1: 173-81, 2000 Apr 01.

Article in En | MEDLINE | ID: mdl-10727416

Subject(s)

Acetylcysteine/pharmacology; Concanavalin A/pharmacology; Lymphocyte Activation; Mitogen-Activated Protein Kinases/metabolism; Reactive Oxygen Species/physiology; T-Lymphocytes/enzymology; Animals; Antioxidants/pharmacology; CD4 Antigens/physiology; CD8 Antigens/physiology; Cells, Cultured; Enzyme Inhibitors/pharmacology; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; Onium Compounds/pharmacology; Phosphorylation; Phosphotyrosine/metabolism; Receptor-CD3 Complex, Antigen, T-Cell/physiology; T-Lymphocytes/drug effects; T-Lymphocytes/immunology; Tetradecanoylphorbol Acetate/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetylcysteine / Lymphocyte Activation / T-Lymphocytes / Reactive Oxygen Species / Concanavalin A / Mitogen-Activated Protein Kinases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biochem J Year: 2000 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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