Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta.

Lin, X; O'Mahony, A; Mu, Y; Geleziunas, R; Greene, W C

Lin, X; O'Mahony, A; Mu, Y; Geleziunas, R; Greene, W C.

Affiliation

Lin X; Gladstone Institute of Virology and Immunology, Departments of Medicine and Microbiology and Immunology, University of California, San Francisco, California 94141, USA.

Mol Cell Biol ; 20(8): 2933-40, 2000 Apr.

Article in En | MEDLINE | ID: mdl-10733597

Subject(s)

CD28 Antigens/metabolism; CD3 Complex/metabolism; Isoenzymes/metabolism; NF-kappa B/metabolism; Protein Kinase C/metabolism; Protein Serine-Threonine Kinases/metabolism; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; I-kappa B Kinase; Isoenzymes/genetics; Jurkat Cells; Mutation; Protein Kinase C/genetics; Protein Kinase C-theta; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C / NF-kappa B / Protein Serine-Threonine Kinases / CD3 Complex / CD28 Antigens / Isoenzymes Limits: Humans Language: En Journal: Mol Cell Biol Year: 2000 Document type: Article Affiliation country: United States

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