Aged mice exhibit greater mortality concomitant to increased brain and plasma TNF-alpha levels following intracerebroventricular injection of lipopolysaccharide.

Kalehua, A N; Taub, D D; Baskar, P V; Hengemihle, J; Muñoz, J; Trambadia, M; Speer, D L; De Simoni, M G; Ingram, D K

Kalehua, A N; Taub, D D; Baskar, P V; Hengemihle, J; Muñoz, J; Trambadia, M; Speer, D L; De Simoni, M G; Ingram, D K.

Affiliation

Kalehua AN; Laboratory of Immunology, Clinical Immunology Section, and Laboratory of Cellular and Molecular Biology, Gerontology Research Center, National Institutes on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

Gerontology ; 46(3): 115-28, 2000.

Article in En | MEDLINE | ID: mdl-10754368

Subject(s)

Aging/metabolism; Brain Diseases/metabolism; Brain Diseases/pathology; Tumor Necrosis Factor-alpha/metabolism; Animals; Brain/metabolism; Brain Diseases/chemically induced; Chi-Square Distribution; Culture Techniques; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Injections, Intraventricular; Interleukin-6/metabolism; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neuroglia/pathology; Reference Values; Survival Analysis

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Brain Diseases / Aging / Tumor Necrosis Factor-alpha Type of study: Prognostic_studies Limits: Animals Language: En Journal: Gerontology Year: 2000 Document type: Article Affiliation country: United States Country of publication: Switzerland

Search on Google

Add to My VHL

XML

PubMed Links