Synthesis and biological evaluation of the four isomers of technetium-99m labeled ethylenecysteamine cysteine ((99m)Tc-ECC), the mono-acid derivative of (99m)tc-L,L-ethylenedicysteine.

Vanbilloen, H P; Cleynhens, B J; Verbruggen, A M

Vanbilloen, H P; Cleynhens, B J; Verbruggen, A M.

Affiliation

Vanbilloen HP; Laboratory of Radiopharmaceutical Chemistry, K.U. Leuven, Belgium.

Nucl Med Biol ; 27(2): 207-14, 2000 Feb.

Article in En | MEDLINE | ID: mdl-10773551

Subject(s)

Cysteine/analogs & derivatives; Organotechnetium Compounds/chemical synthesis; Radiopharmaceuticals/chemical synthesis; Adult; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cysteine/blood; Cysteine/chemical synthesis; Cysteine/pharmacokinetics; Electrophoresis, Paper; Humans; Isotope Labeling; Kidney/metabolism; Male; Mice; Organotechnetium Compounds/blood; Organotechnetium Compounds/pharmacokinetics; Papio; Probenecid/pharmacology; Protein Binding; Radioisotope Renography; Radiopharmaceuticals/blood; Radiopharmaceuticals/pharmacokinetics; Renal Agents/pharmacology; Stereoisomerism; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Organotechnetium Compounds / Radiopharmaceuticals / Cysteine Limits: Adult / Animals / Humans / Male Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2000 Document type: Article Affiliation country: Belgium

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