Knockout of the murine prostaglandin EP2 receptor impairs osteoclastogenesis in vitro.

Li, X; Okada, Y; Pilbeam, C C; Lorenzo, J A; Kennedy, C R; Breyer, R M; Raisz, L G

Li, X; Okada, Y; Pilbeam, C C; Lorenzo, J A; Kennedy, C R; Breyer, R M; Raisz, L G.

Affiliation

Li X; Department of Medicine, University of Connecticut Health Center, Farmington 06030, USA.

Endocrinology ; 141(6): 2054-61, 2000 Jun.

Article in En | MEDLINE | ID: mdl-10830290

Subject(s)

Osteoclasts/physiology; Receptors, Prostaglandin E/physiology; Acid Phosphatase/analysis; Animals; Bone Marrow Cells/metabolism; Calcitriol/pharmacology; Carrier Proteins/genetics; Cells, Cultured; Coculture Techniques; Dinoprostone/pharmacology; Female; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology; Isoenzymes/analysis; Male; Membrane Glycoproteins/genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteoblasts/metabolism; Parathyroid Hormone/pharmacology; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Prostaglandin E/deficiency; Receptors, Prostaglandin E/genetics; Receptors, Prostaglandin E, EP2 Subtype; Spleen/metabolism; Tartrate-Resistant Acid Phosphatase

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Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Receptors, Prostaglandin E Limits: Animals Language: En Journal: Endocrinology Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

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