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Mycalamide D, a new cytotoxic amide from the New Zealand marine sponge Mycale species.
West, L M; Northcote, P T; Hood, K A; Miller, J H; Page, M J.
Affiliation
  • West LM; School of Chemical and Physical Sciences, Victoria University of Wellington, New Zealand.
J Nat Prod ; 63(5): 707-9, 2000 May.
Article in En | MEDLINE | ID: mdl-10843597
ABSTRACT
A new mycalamide, mycalamide D (3), has been isolated from the New Zealand marine sponge Mycale sp. This new metabolite, in which the C13-O-methyl group of mycalamide A (1) is replaced by a hydrogen atom, was found to be cytotoxic to a range of mammalian cell lines, with a potency approximately 20-fold less than that of 1.
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Collection: 01-internacional Database: MEDLINE Main subject: Porifera / Pyrans / Antineoplastic Agents Limits: Animals / Humans Country/Region as subject: Oceania Language: En Journal: J Nat Prod Year: 2000 Document type: Article Affiliation country: New Zealand
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Collection: 01-internacional Database: MEDLINE Main subject: Porifera / Pyrans / Antineoplastic Agents Limits: Animals / Humans Country/Region as subject: Oceania Language: En Journal: J Nat Prod Year: 2000 Document type: Article Affiliation country: New Zealand