Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity.

Keren, P; George, J; Shaish, A; Levkovitz, H; Janakovic, Z; Afek, A; Goldberg, I; Kopolovic, J; Keren, G; Harats, D

Keren, P; George, J; Shaish, A; Levkovitz, H; Janakovic, Z; Afek, A; Goldberg, I; Kopolovic, J; Keren, G; Harats, D.

Affiliation

Keren P; Institute of Lipid and Atherosclerosis Research, Sheba Medical Center, Tel-Hashomer, Israel.

Diabetes ; 49(6): 1064-9, 2000 Jun.

Article in En | MEDLINE | ID: mdl-10866061

Subject(s)

Arteriosclerosis/complications; Bacterial Proteins; Hyperglycemia/complications; Hyperlipidemias/complications; Receptors, LDL/deficiency; Animals; Antibodies/analysis; Aorta/pathology; Arteriosclerosis/pathology; Blood Glucose/analysis; Body Weight; Chaperonin 60; Chaperonins/immunology; Cytokines/biosynthesis; Female; Hyperglycemia/blood; Hyperglycemia/chemically induced; Hyperglycemia/immunology; Hyperlipidemias/blood; Hyperlipidemias/chemically induced; Hyperlipidemias/immunology; Immunity; Immunity, Cellular; Lipids/blood; Lipoproteins, LDL/immunology; Male; Mice; Mice, Inbred C57BL; Spleen/immunology; Spleen/metabolism; Spleen/pathology; Streptozocin

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Collection: 01-internacional Database: MEDLINE Main subject: Arteriosclerosis / Bacterial Proteins / Receptors, LDL / Hyperglycemia / Hyperlipidemias Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Diabetes Year: 2000 Document type: Article Affiliation country: Israel Country of publication: United States

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