SB-203207 and SB-203208, two novel isoleucyl tRNA synthetase inhibitors from a Streptomyces sp. II. Structure determination.

Houge-Frydrych, C S; Gilpin, M L; Skett, P W; Tyler, J W

Houge-Frydrych, C S; Gilpin, M L; Skett, P W; Tyler, J W.

Affiliation

Houge-Frydrych CS; SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Harlow, Essex, UK.

J Antibiot (Tokyo) ; 53(4): 364-72, 2000 Apr.

Article in En | MEDLINE | ID: mdl-10866218

Subject(s)

Alkaloids/chemistry; Antibiotics, Antineoplastic/chemistry; Enzyme Inhibitors/chemistry; Indenes/chemistry; Pyridines; Sulfonamides/chemistry; Sulfur Compounds; Chromatography, High Pressure Liquid; Enzyme Inhibitors/pharmacology; Hydrolysis; Indenes/pharmacology; Isoleucine-tRNA Ligase/antagonists & inhibitors; Magnetic Resonance Spectroscopy; Molecular Structure; Streptomyces; Sulfonamides/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Sulfonamides / Sulfur Compounds / Alkaloids / Enzyme Inhibitors / Indenes / Antibiotics, Antineoplastic Language: En Journal: J Antibiot (Tokyo) Year: 2000 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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