Mono- and biphasic plasma concentration-time curves of mesalazine from a 500 mg suppository in healthy male volunteers controlled by the time of defecation before dosing.

Vree, T B; Dammers, E; Exler, P S; Maes, R A

Vree, T B; Dammers, E; Exler, P S; Maes, R A.

Affiliation

Vree TB; Institute for Anaesthesiology, Academic Hospital Nijmegen Sint Radboud, Nijmegen, The Netherlands. T.Vree@anes.azn.nl

J Pharm Pharmacol ; 52(6): 645-52, 2000 Jun.

Article in En | MEDLINE | ID: mdl-10875540

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/pharmacokinetics; Mesalamine/pharmacokinetics; Absorption; Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Defecation; Humans; Male; Mesalamine/administration & dosage; Suppositories; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Mesalamine Type of study: Prognostic_studies Limits: Adult / Humans / Male Language: En Journal: J Pharm Pharmacol Year: 2000 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

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