Suppression of the rat microglia Kv1.3 current by src-family tyrosine kinases and oxygen/glucose deprivation.

Cayabyab, F S; Khanna, R; Jones, O T; Schlichter, L C

Cayabyab, F S; Khanna, R; Jones, O T; Schlichter, L C.

Affiliation

Cayabyab FS; Division of Cellular and Molecular Biology, Toronto Western Research Institute, University Health Network, Toronto, Canada.

Eur J Neurosci ; 12(6): 1949-60, 2000 Jun.

Article in En | MEDLINE | ID: mdl-10886336

Subject(s)

Glucose/pharmacology; Microglia/enzymology; Oxygen/pharmacology; Potassium Channels, Voltage-Gated; Potassium Channels/metabolism; src-Family Kinases/metabolism; Animals; Animals, Newborn; Brain/cytology; Cells, Cultured; Disks Large Homolog 4 Protein; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Kv1.3 Potassium Channel; Membrane Potentials/drug effects; Membrane Potentials/physiology; Membrane Proteins; Microglia/cytology; Microglia/drug effects; Nerve Tissue Proteins/genetics; Oncogene Protein pp60(v-src)/genetics; Oncogene Protein pp60(v-src)/metabolism; Oxidative Stress/physiology; Patch-Clamp Techniques; Phosphorylation; Potassium Channels/genetics; Rats; Rats, Wistar; Scorpion Venoms/pharmacology; Transfection; Tyrosine/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Potassium Channels / Microglia / Src-Family Kinases / Potassium Channels, Voltage-Gated / Glucose Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Neurosci Journal subject: NEUROLOGIA Year: 2000 Document type: Article Affiliation country: Canada

Search on Google

Add to My VHL

XML

PubMed Links