Meningeal carcinomatosis manifested as bilateral progressive sensorineural hearing loss.
Am J Otol
; 21(4): 510-2, 2000 Jul.
Article
in En
| MEDLINE
| ID: mdl-10912696
OBJECTIVE: Meningeal carcinomatosis is defined as the diffuse infiltration of the leptomeninges and subarachnoid space by malignant cells metastasizing from systemic cancer. The authors describe a rare case of meningeal carcinomatosis initially appearing as bilateral progressive sensorineural hearing loss. PATIENT: A 57-year-old man with lung cancer was referred to the authors' clinic because of progressive hearing loss, tinnitus, dizziness, and blurred vision for 1 month. RESULTS: Magnetic resonance imaging revealed abnormal leptomeningeal enhancement. Meningeal carcinomatosis was diagnosed by the detection of malignant cells in the cerebrospinal fluid after lumbar puncture. The patient died 1 year after diagnosis. CONCLUSIONS: Meningeal carcinomatosis must be considered in the differential diagnosis in cancer patients with bilateral progressive sensorineural hearing loss. Gadolinium-enhanced magnetic resonance imaging is a useful complementary diagnostic tool before lumbar puncture.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adenocarcinoma
/
Hearing Loss, Sensorineural
/
Lung Neoplasms
/
Meningeal Neoplasms
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Am J Otol
Year:
2000
Document type:
Article
Country of publication:
United States