p53 but not bcl-2 immunostaining is predictive of poor clinical complete response to primary chemotherapy in breast cancer patients.

Bottini, A; Berruti, A; Bersiga, A; Brizzi, M P; Brunelli, A; Gorzegno, G; DiMarco, B; Aguggini, S; Bolsi, G; Cirillo, F; Filippini, L; Betri, E; Bertoli, G; Alquati, P; Dogliotti, L

Bottini, A; Berruti, A; Bersiga, A; Brizzi, M P; Brunelli, A; Gorzegno, G; DiMarco, B; Aguggini, S; Bolsi, G; Cirillo, F; Filippini, L; Betri, E; Bertoli, G; Alquati, P; Dogliotti, L.

Affiliation

Bottini A; Centro di Senologia, Cremona, Italy.

Clin Cancer Res ; 6(7): 2751-8, 2000 Jul.

Article in En | MEDLINE | ID: mdl-10914720

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Breast Neoplasms/drug therapy; Epirubicin/therapeutic use; Proto-Oncogene Proteins c-bcl-2/analysis; Tamoxifen/therapeutic use; Tumor Suppressor Protein p53/analysis; Adult; Aged; Breast Neoplasms/pathology; Breast Neoplasms/surgery; Cyclophosphamide/administration & dosage; Female; Fluorouracil/administration & dosage; Humans; Immunohistochemistry/methods; Methotrexate/administration & dosage; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Receptor, ErbB-2/analysis; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Tamoxifen / Breast Neoplasms / Epirubicin / Antineoplastic Combined Chemotherapy Protocols / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-bcl-2 Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2000 Document type: Article Affiliation country: Italy Country of publication: United States

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