CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection.

Delgado, P; Fernández, E; Dave, V; Kappes, D; Alarcón, B

Delgado, P; Fernández, E; Dave, V; Kappes, D; Alarcón, B.

Affiliation

Delgado P; Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Spain.

Nature ; 406(6794): 426-30, 2000 Jul 27.

Article in En | MEDLINE | ID: mdl-10935641

Subject(s)

Adaptor Proteins, Signal Transducing; CD3 Complex/metabolism; Membrane Proteins; Mitogen-Activated Protein Kinases/metabolism; Receptors, Antigen, T-Cell/metabolism; Thymus Gland/cytology; Animals; Carrier Proteins/metabolism; Cells, Cultured; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Lipids/metabolism; Mice; Phosphoproteins/metabolism; Signal Transduction; T-Lymphocytes/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Thymus Gland / Receptors, Antigen, T-Cell / CD3 Complex / Mitogen-Activated Protein Kinases / Adaptor Proteins, Signal Transducing / Membrane Proteins Limits: Animals Language: En Journal: Nature Year: 2000 Document type: Article Affiliation country: Spain

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